Uji Ekstrak Daun Cemcem Dalam Menghambat Pertumbuhan Bakteri Phorphyromonas Gingivalis
DOI:
https://doi.org/10.23887/jstundiksha.v11i2.49457Kata Kunci:
Cemcem, Spondias pinnata, Phorphyromonas gingivalisAbstrak
Cemcem atau Spondias pinnata (L.f) Kurz merupakan tanaman yang banyak digunakan oleh masyarakat Bali sebagai obat tradisional secara turun temurun. Beberapa penelitian telah dilakukan dan didapatkan bahwa ekstrak daun Cemcem memiliki aktivitas antibakteri. P. gingivalis merupakan salah satu penyebab periodontitis. Periodontitis merupakan penyakit gigi dan mulut yang banyak dialami oleh masyarakat Indonesia. Tujuan dari penelitian ini adalah untuk mengetahui kandungan senyawa bioaktif dan daya hambat ekstrak etanol daun Cemcem terhadap pertumbuhan P. gingivalis. Untuk mengetahui kandungan senyawa bioaktif dilakukan uji terhadap alkaloid, flavonoid, terpenoid, steroid, dan tannin. Uji daya hambat ekstrak etanol daun Cemcem dilakukan menggunakan metode difusi cakram dengan kontrol positif yaitu chlorhexidine 2%, kontrol negatif yaitu etanol, serta dua konsentrasi ekstrak yaitu 60% dan 80%. Dari hasil penelitian diperoleh bahwa ekstrak etanol daun Cemcem mengandung senyawa alkaloid, flavonoid, steroid, dan tannin. Zona hambat yang terbentuk memilki perbedaan bermakna antara ketiga perlakuan dan masuk dalam kategori kuat.
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